SPHINGOSINE-1-PHOSPHATE SECRETS

Minimal concentrations of S1P are chemotactic for osteoclast precursors, although large concentrations inhibit their movement seventy nine. This means that these precursors, which Specific both S1PR1 and S1PR2, are stored in the vicinity of your bone because of the S1P gradient: S1PR2 stops S1PR1-induced migration of such bone-resorbing cells from